A wound, regardless of the reason for its formation, has to undergo the natural healing process. The wound is the disruption of the physical function and structure of the skin and its soft tissues that are underlying.The healing process involves hemostasis, inflammation, epithelialization, fibroplasia, and maturation. When there is a slowdown in the pattern, or when the process stops in the middle, it is a sign of an underlying condition.
This can be a result of the peripheral artery disease, diabetes, lack of blood flow, or the diseases of various other organs.
When a wound occurs, the blood flow to the skin is controlled over a period of time, and this leads to ischemic breakdown. When the healing process is in the stage of inflammation, the progress is stopped most of the times. The reason may be thepresence of bacteria, any foreign material, or necrotic tissue. In thecase of any of these, inflammation balance is lost. This results in the impairment of cytokine release. This leads to the closing of the wound, or the next step called re-epithelialization is delayed. Unfortunately, it is not known till the last step arrives.
UV Light Therapy in Non-healing Wounds
Cells present in the body are of hundreds of types. With much more thousands of the biological molecules present, any treatment to get a right solution might hinder the other processes carried forward by these cells. Fortunately, the UV light therapy has proved to be beneficial. This lets the body tissues to grow and attach to the new cells.
During research, when the UV light was shown on the gel, the inhibitor cell molecules that was inhibiting RGD peptide was dropped off, and the peptide again became active. Sometimes a weak immune response is needed when some biomaterials are introduced in the body, so these inhibitors help in shutting down the signaling of peptide molecules and the peptide is left in an inactive stage. It helps in maintaining the controlled approach where the precise timing for peptide signaling is needed.
The research is going on in the animal models. But when done with the humans, it is very well seen that the cell process is, even more, faster, and can offer better results. This means a ray of light, through the UV light, can be seen to improve success rates in immunology, regenerative medicine, cell damage, and cancer-related treatments. Of course, the same can help in hastening the wound healing process too.
When UV light is used, the process has to be controlled actively. In fact, this is the truth for all the biological processes. There are positive responses to implanted materials when UV light is used for therapy in which the drug is given to turn off the signal and then turn on the signals at the precise time using light.So medical intervention becomes mandatory when UV light therapy is carried out.
You need to follow up with the doctor, and the treatment involves taking out the blood from the veins. The blood is allowed to pass through UV, and the same is injected into the patient again. There are also handheld devices, and combs used for various treatments. The doctor has to decide which is the best option for you. You need to wait for at least 10 to 12 sessions of UV treatment to see the results. You can opt for the home treatment sessions if the doctor feels it is feasible.